DOI: http://dx.doi.org/10.18203/issn.2454-5929.ijohns20190763

Assess the outcome of pre and postoperative bacterial culture in sinonasal polyposis cases under FESS

C. P. Sudheer, T. Dinesh Singh

Abstract


Background: Sinonasal polyposis is multifactorial condition characterised by mucous membrane lesions in nose and paranasal sinuses. Pre and post-operative management of cases undergoing functional endoscopic sinus surgery (FESS) give ideal surgical outcome. This study designed to assess pre and postoperative bacterial profile in sinonasal polyposis cases undergoing Functional endoscopic sinus surgery.

Methods: A total 100 cases ready for endonasal endoscopic surgery with chief complaints of sinonasal polyposis were recruited for the study. Pre and post-operative nasal swabs were collected from lateral wall, floor and area over the polyps. Sensitivity test was performed by using commonly available antibiotics i.e. ceftriaxone, erythromycin, ampicillin, gentamycin, ciprofloxacin, cephalexin, doxycycline and co-trimoxazole.  

Results: Pre-operative bacterial culture showed growth of Staphylococcus coagulase negative (CONS) in 32% cases, Staphylococcus aureus in 24%. Post-operative bacteria culture showed Staphylococcus coagulase negative (CONS) in 22% cases, Staphylococcus aureus in 22% cases. Staphylococcus coagulase negative (CONS) and Staphylococcus aureus had resistance to Ampicillin and Gentamycin.

Conclusions: Staphylococcus coagulase negative (CONS) and Staphylococcus aureus are isolated commonly in pre and post-operative bacteria culture. Ampicillin, gentamicin, cefotaxime and ceftriaxone are primary choice for intravenous antibiotics in current clinical practice and in al surgical procedures including endoscopic sinus procedures.


Keywords


Sinonasal polyposis, Functional endoscopic sinus surgery, Antibiotic sensitivity, Staphylococcus coagulase negative, Staphylococcus aureus

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References


Samantaray K, Pradhan N, Biswal R. An overview of sinonasal polyposis: a prospective study. J Evid Based Med Healthc. 2016;3(31):1391-5.

Zafar U, Khan N, Afroz N, Hasan SA. Clinico-pathological study of non-neoplastic lesions of nasal cavity and paranasal sinuses. Indian J Pathol Microbiol. 2008;51(1):26-9.

Kumari KMK, Mahadeva KC. Polypoidal lesions in the nasal cavities. J Clin Diag Res. 2013;7(6):1040-2.

Tysome J. Sharp H. Current Trends in Pre and Postoperative Management of Functional Endoscopic Sinus Surgery. J Otorhinolaryng. 2005;5(2):1-7.

Stammberger H. Surgical treatment of nasal polyps:past, present and future. Allergy. 1999;54:7-11.

Watelet JB, Annicq B, van Cauwenberge P, Bachert C. Objective outcome after functional endoscopic sinus surgery: prediction factors. Laryngoscope. 2004;114:1092-7.

Friedmann I. Inflammatory conditions of the nose. In: Symmers WSTC, ed. Nose, throat and ears. 3rd ed. Edinburgh: Churchill Livingstone; 1986: 19-23.

Newton JR, Ah-See KW. A review of nasal polyposis. Ther Clin Risk Manag. 2008;4(2):507-12.

Bloom SM. Nasal polyps. J Asthma Res. 1969;6:137.

Smith AC, Homick RB. Invasion of a nasal polyp by Elastomjces dermafitidis. Washington, DC: American Society for Microbiology; 1978: 319.

Zernotti ME, Villegas NA, Revol MR, Baena-Cagnani CE, Miranda JEA, Paredes ME, et al. Evidence of Bacterial Biofi lms in Nasal Polyposis. J Investig Allergol Clin Immunol. 2010;20(5):380-5.