DOI: http://dx.doi.org/10.18203/issn.2454-5929.ijohns20190067

A study of oral lesions among HIV infected ENT patients

G. Soundara Rajan, D. Senthamarai Kannan

Abstract


Background: Oral lesions are the earliest and most important indicators of HIV infection. These lesions may be present in up to 50% of people with HIV infection. The lesions parallel the decline in number of CD4+ cells and an increase in viral load, and are also independent indicators of disease progression. Pseudomembranous candidiasis and hairy leukoplakia are considered as the most common lesion associated with HIV infection.

Methods: This cross sectional descriptive study was done in our ENT op during the period of 3 years. All HIV reactive patients who came to our OPD were included in the study. Oral examination was carried out using Bull’s eye lamp.  

Results: Totally 123 patients of HIV came to ENT OPD during the period of 3 years. Among them 52 patients (42.5%) showed one or many oral lesions. The presence of oral lesions has a significant impact on health related quality of life. The commonest oral lesion noted in our study is oral candidiasis (50%).

Conclusions: Early detection of oral lesions must be emphasized in the diagnosis and early management of HIV patients.


Keywords


Pseudomembranous candidiasis, Oral hairy leukoplakia, CD4 count

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References


Palmer GD, Robinson PG, Challacombe SJ, Birnbaum W, Croser D, Erridge PL, et al. Aetiological factors for oral manifestations of HIV infection. Oral Diseases. 1996;2:193-7.

Lifson AR, Hilton JF, Westenhouse JL, Canchola AJ, Samuel MC, Katz MH, et al. Time from HIV seroconversion to oral candidiasis or hairy leukoplakia among homosexual and bisexual men enrolled in three prospective cohorts. AIDS. 1994;8:73-9.

Greenspan JS, Greenspan D. The epidemiology of the oral lesions of HIV infection in the developed world. Oral Diseases. 2002;8(2):34-9.

Marcenes W, Pankhurst CL, Lewis DA. Oral health behaviour and the prevalence of oral manifestations of HIV infection in a group of HIV positive adults. Int Dent J. 1998;48(6):557-62.

Mbopi-Keou FX, Mbu RE, Gonsu Kamga H, Kalla GC, Monny Lobe M, Teo CG, et al. Interactions between human immunodeficiency virus and herpes viruses within the oral mucosa. Clin Microbiol Infect. 2005;11(2):83-5.

Neville BW, Damm DD, Allen CM, Bouquot JE. Oral and maxillofacial pathology. Philladelphia: Saunders Company; 1995.

Coulter ID, Heslin KC, Marcus M, Hays RD, Freed J, Der-Martirosia C, et al. Associations of self-reported oral health with physical and mental health in a nationally representative sample of HIV persons receiving medical care. Qual Life Res. 2002;11:57-60.

Greenspan JS, Greenspan D. The epidemiology of the oral lesions of HIV infection in the developed world. Oral Dis. 2002;8(2):34-9.

Anil S, Challacombe SJ. Oral lesions of HIV and AIDS in Asia: an overview. Oral Dis. 1997;3:S36–40.

Ranganathan K, Reddy BV, Kumarasamy N, Solomon S, Viswanathan R, Johnson NW. Oral lesions and conditions associated with human immunodeficiency virus infection in 300 south Indian patients. Oral Dis. 2000;6:152–7.

Sen S, Mandal S, Bhattacharya S, Halder S, Bhaumik P. Oral manifestations in human immunodeficiency virus infected patients. Indian J Dermatol. 2010;55(1):116-8.

Lamster IB, Begg MD, Mitchell-Lewis D, Fine JB, Grbic JT, Todak GG, et al. Oral manifestations of HIV infection in homosexual men and intravenous drug users. Study design and relationship of epidemiologic, clinical, and immunologic parameters to oral lesions. Oral Surg Oral Med Oral Pathol. 1994;78:163-74.

Kerdpon D, Pongsiriwet S, Pangsomboon K, Iamaroon A, Kampoo K, Sretrirutchai S, et al. Oral manifestations of HIV infection in relation to clinical and CD4 immunological status in northern and southern Thai patients. Oral Dis. 2004;10:138-44.

Hodgson TA. HIV-associated oral lesions: prevalence in Zambia. Oral Dis. 1997;3:S46-50.

Patton LL, McKaig RG, Strauss RP, Eron JJ. Oral manifestations of HIV in a southeast USA population. Oral Dis. 1998;4:164-9.

Tsang PC, Samaranayake LP. Oral manifestations of HIV infection in a group of predominantly ethnic Chinese. J Oral Pathol Med. 1999;28:122-7.

Arendorf T, Holmes H. Oral manifestations associated with human immunodeficiency virus (HIV) infection in developing countries-are there differences from developed countries? Oral Dis. 2000;6:133–5.