Clinico-pathological and radiological correlation of sino-nasal masses in a tertiary care center

Authors

  • Dimple Sahni Department of ENT, Government Medical College, Patiala, Punjab, India
  • Gagandeep Kaur Department of ENT, Government Medical College, Patiala, Punjab, India
  • Peeyush Verma Department of ENT, Government Medical College, Patiala, Punjab, India
  • Rajwant Kaur Department of ENT, Government Medical College, Patiala, Punjab, India
  • Harpal Singh Department of Pathology, Government Medical College, Patiala, Punjab, India

DOI:

https://doi.org/10.18203/issn.2454-5929.ijohns20202790

Keywords:

Sino nasal mass, Neoplastic, Non-neoplastic, Histopathological, Polyp

Abstract

Background: The nasal masses are most commonly encountered condition in outpatient department of otorhinolaryngology. The purpose of this study was to show the clinical, radiological and histopathological correlation of sino nasal masses.

Methods: This study was conducted on 100 cases with sino nasal masses over a period of 2 years. A provisional diagnosis was made after clinical and radiological investigation which was confirmed with histopathological examination and the findings were correlated.  

Results: The number of non-neoplastic lesions were more than neoplastic lesions (75% vs 25%). Incidence was highest in the age group of 31-40 year (21%) with male to female ratio of 1.5:1. In our study among non-neoplastic lesion, inflammatory lesion had highest frequency (75%). We found clinical and histopathological correlation in 94.6% cases (p value 0.04). 93.33% cases correlated radiologically and histopathologically (p value 0.04).    

Conclusions: We concluded that for proper evaluation of sino nasal masses, clinical, radiological, histopathological evaluation should be carried out conjointly. Histopathologic evaluation remains the gold standard.

References

Llorente JL, Lopez F, Suarez C, Hermsen MA. Sinonasal carcinoma: clinical, pathological, genetic and therapeutic advances. Nature Rev Clin Oncol. 2014;11(8):460.

Das S, Kirsch CF. Imaging of lumps and bumps in the nose: A review of sino nasal tumours. Cancer Imaging. 2005;5:167‑77.

Thompson LD. Sino nasal carcinomas. Current Diagnostic Pathology. 2006;12(1):40-53.

Newton JR, See AKW. A review of nasal polyposis. Therapeutics Clin Risk Management. 2008;4(2):507-12.

Sharma A, Garg LN, Baisakhiya N. Clinico-pathological and radiological assessment of benign nasal masses. Int J Otorhinolaryngol Head Neck Surg. 2017;3:1087-94.

Carrau RL, Myers EM, Johnson JT. Paranasal sinus carcinoma: diagnosis, treatment and prognosis. Oncology (Williston Park, NY). 1992;6(1):43-50.

Spiro JD, Soo KC, Spiro RH. Non-squamous cell malignant neoplasms ODF the nasal cavities and paranasal sinuses. Head Neck. 1995;17(2):114-8.

Turner JH, Reh DD. Incidence and survival in patients with sino nasal cancer: a historical analysis of population-based data. Head Neck. 2012;34(6):877-85.

Boffetta P, Boccia S, Vecchia LC. A quick guide to cancer epidemiology; Epidemiology, Biostatistics and Public Health. Overview Major Causes Human Cancer. 2014;11(1):77-88.

Maheshwari A, Bansal A. Clinico-pathological spectrum of sino nasal masses: a tertiary care hospital experience. Int J Otorhinolaryngol Head Neck Surg. 2017;3(4):1015.

Bist SS, Varshney S, Baunthiyal V, Bhagat S, Kusum A. Clinico-pathological profile of sino nasal masses: an experience in tertiary care hospital of Uttarakhand. Natl J Maxillofac Surg. 2012;3:180-6.

Sharma R, Sahni D, Uppal K, Gupta R, Singla G. A clinicopathological study of masses of nasal cavity paranasal sinuses and nasopharynx. Int J Otorhinolaryngol Head Neck Surg. 2017;3(2):253.

Lathi A, Syed MM, Kalakoti P, Qutub D, Kishve SP. Clinico-pathological profile of sino nasal masses: a study from a tertiary care hospital of India. ACTA Otorhinolaryngologicaitalica. 2011;31(6):372.

Sharma A, Garg LN, Baisakhiya N. Clinico-pathological and radiological assessment of benign nasal masses. Int J Otorhinolaryngol Head Neck Surg. 2017;3:1087-94.

Khan N, Zafar U, Afroz N, Ahmad SS, Hasan SA. Masses of nasal cavity, paranasal sinuses and nasopharynx: a clinicopathological study. Indian J Otolaryngol Head Neck Surg. 2006;58:259‑63.

Dhillon V, Dhingra R, Davessar JL, Chaudhary A, Monga S, Kaur M, et al. Correlation of clinical, radiological and histopathological diagnosis among patients with sino nasal masses. Int J Contemporary Med Res. 2016;3(6):1612-5.

Karki R, Pradhan B, Thapa N, Jha A. Correlation of clinical and radiological with post-operative histopathological diagnosis of nasal masses. Nepalese J ENT Head Neck Surg. 2012;3(1):5-6.

Gupta R, Moupachi SS, Poorey VK. Sino nasal masses: a retrospective analysis. Indian J Otolaryngol Head Neck Surg. 2013;65(1):52-6.

Kale SU, Mohite U, Rowlans D, Lee DAB. Clinical and histopathological correlation of nasal polyps; Are there any surprises. Clin Otolaryngol Allied Sci. 2001;26:321-3.

Diamantopoulus II, Jones NS, Lowe J. All nasal polyps need histological examination: An audit-based appraisal of clinical practice. J Laryngol Otol. 2000:114:755-9.

Downloads

Published

2020-06-25

Issue

Section

Original Research Articles