DOI: http://dx.doi.org/10.18203/issn.2454-5929.ijohns20213293

Carcinosarcoma of the nasopharynx: a case report

Monica Kotu, Ian Paul Olwoch, Thabo Kgomo

Abstract


Carcinosarcoma is a malignant tumor with a dual histological appearance, a squamous epithelial (sarcomatous), and a mesenchymal component. Carcinosarcomas are characterized by a high recurrence rate, metastatic spread, and high morbidity and mortality. Carcinosarcoma can arise from any squamous epithelial lining but rare in the sino-nasal tract. We are presenting a case of a 19-year-old male with a 3-month history of recurrent epistaxis associated with nasal blockage, anosmia, and bilateral complete loss of vision over a few weeks. Carcinosarcoma of the sino-nasal tract is a rare entity and can mimic any sino-nasal malignancy. The optimal treatment of this disease is controversial and lacks a clear guideline, therefore challenging to the treating oncologists. Carcinosarcoma of the head and neck is a rare and aggressive tumor. It poses diagnostic and treatment challenges.


Keywords


Carcinosarcoma, Nasopharynx, Sinonasal malignancy

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References


Saphir O, Vass A. Carcinosarcoma. Am J Cancer. 1938;33:331-61.

Singh G, Sharma D. Carcinosarcoma of head and neck; clinicopathological characteristics, treatment, and outcomes of unique neoplasm. Int J Radiol Radiat Ther. 2017;3(5):269-70.

Said MS. True Malignant mixed tumor (Carcinosarcoma). Medscape reference. 2015.

Patel TD. A case control-analysis of survival outcomes in sino-nasal carcinosarcoma. Am J Otolaryngol. 2015;36:200-04.

Lim AL, Zahirrudin Z. A rare case of Nasopharyngeal Carcinosarcoma. Med J Malaysia. 2012;67:428-9.

Kumar T, Kothari K. Carcinosarcoma of upper aero-digestive tract: A case study. Indian J Surg Oncol. 2011;2(4):316-31.

Dhruba JT, Mittal RS, Sharma A. Sino-nasal terato-carcinosarcoma involving nasal cavity, nasopharynx, and all paranasal sinuses with bilateral orbital and intracranial extension: A rare case report. Asian J Neurosurg. 2017;12:232-40.

De Cruz S. A rare case of invasive sino-nasal carcinosarcoma. Int J Surg. 2020;70:243-8.

Hasnaoui J. Carcinosarcoma of the maxillary sinus: A rare case report. Annals of Med Surg. 2017;19: 41-4.

Yuen J, Varadarajan V, Stavrakas M, Muquit S, Khalil H. A case of Invasive Sino-nasal Carcinosarcoma: The importance of early detection. Case Rep Otolaryngol. 2018;274-6.