DOI: http://dx.doi.org/10.18203/issn.2454-5929.ijohns20214063

Use of Triamcinolone in keloid

Shwetha B., Sathyaki D. C.

Abstract


Background: Keloids are well known for recurrence. There is no standardized regimen for the treatment of keloids. Many different treatment modalities such as surgical excision, intralesional corticosteroids, radiotherapy, and pressure earrings have been used for keloids. Surgical excision alone may result in recurrence rate of 40-100%. Many different modalities of treatment have been tried to prevent recurrence. Aims and objectives of the study was to evaluate the efficacy of Triamcinolone in preventing recurrence of Keloid.

Methods: 40 patients who underwent excision of keloid at a tertiary care centre. Surgery alone was performed in 20 patients and surgery with post operative intra lesional Triamcinolone injection was given weekly interval for 6 weeks in another 20 patients. Patients were followed up for the period of 2 years

Results: Recurrence was found in 5 patients who underwent excision alone and there was no recurrence among patients who received post operative intra lesional triamcinolone.

Conclusions: Multi modality treatment is better to prevent recurrence of Keloid.


Keywords


Keloid, excision, Triamncinolone

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References


Guo L, Xu K, Yan H, Feng H, Chai L, Xu G. Expression Profile of Long Noncoding RNAs in Human Earlobe Keloids: A Microarray Analysis. Biomed Res Int. 2016;1:1-4.

Pierce HE. Keloids: enigma of the plastic surgeon. Journal of national medical association. 1979;71(12):1177-80.

Metts J. Common complications of body piercing. West J Med. 2002;176(2):85-6.

Sand M, Sand D, Boorboor P, Mann B, Altmeyer P, Hoffmann K et al. Combination of surgical excision and custom designed silicon pressure splint therapy for keloids on the helical rim. Head Face Med. 2007;3:14.

Bashir MM, Ahmad H, Yousaf N, Khan FA. Comparison of single intra operative versus an intra operative and two post operative injections of the triamcinolone after wedge excision of keloids of helix. Journal of Pakistan medical association. 2015;65(7):737-41.

Hietanen KE, Järvinen TA, Huhtala H, Tolonen TT, Kuokkanen HO, Kaartinen IS. Treatment of keloid scars with intralesional Triamcinolone and 5-fluorouracil injections: A ramdomized controlled trail. J Plast Reconstr Aesthet Surg. 2019;72(1):4-11.

Khalid FA, Mehrose MY, Saleem M, Yousaf MA, Mujahid AM, Rehman SU et al. Comparison of efficacy and safety of intralesional triamcinolone and combination of triamcinolone with 5-fluorouracil in the treatment of keloids and hypertrophic scars: Randomised control trial. Burns. 2019;45(1):69-75.

Limmer EE, Glass DA. A Review of Current Keloid Management: Mainstay Monotherapies and Emerging Approaches. Dermatol Ther (Heidelb). 2020;10(5):931-48.