Comparative study of fine needle aspiration cytology and histopathology of thyroid swellings in tertiary health centre

Authors

  • Gangadhara K. S. Department of ENT, McGann Teaching District Hospital, Shimoga Institute of Medical Siences, Shivamogga, Karnataka, India
  • Chaitanya Vadva Department of ENT, McGann Teaching District Hospital, Shimoga Institute of Medical Siences, Shivamogga, Karnataka, India
  • Sridhara S. Department of ENT, McGann Teaching District Hospital, Shimoga Institute of Medical Siences, Shivamogga, Karnataka, India

DOI:

https://doi.org/10.18203/issn.2454-5929.ijohns20214900

Keywords:

Thyroid swelling, FNAC, Accuracy, Sensitivity, Specificity

Abstract

Background: Thyroid swelling being the most common presentation in ENT clinical practice, a prospective study was done to assess the role of Fine needle aspiration cytology in diagnosing the nature of thyroid swellings and comparing its results with histopathological examination findings.

Methods: This is a prospective institutional based study comparing cytology and corresponding histopathology findings reported in 60 cases of thyroid swelling. The statistical analysis included sensitivity, specificity, positive predictive value, negative predictive value and accuracy in thyroid swelling.

Results: Out of 60 cases, FNAC showed 93.3% and 6.6% of benign and malignant cases respectively whereas HPE showed 86.7% and 13.3% of benign and malignant cases respectively. On FNAC-HPE correlation using HPE as standard reference the diagnostic accuracy of present study is 91.66%.

Conclusions: It was observed that FNAC is a reliable tool, safe and accurate method in evaluating thyroid swelling thus having great influences in treatment decision. Thus FNAC is the investigation of choice in thyroid swellings with excellent patient compliance, simple, safe and cost effective.

References

Kumar A, Rout K, Ray CS, Behera SK, Biswal R. A Comparative Study of FNAC and Histopathology of Thyroid Swellings. Indian J Otolaryngol Head Neck Surg. 2011;63(4):370-2.

Sengupta A, Pal R, Kar S, Zaman FA, Basu M, Pal S. Clinico-pathological correlates of incidentally revealed thyroid swelling in Bihar, India. J Pharm Bioallied Sci. 2012;4(1):51-5.

Mangshetty SS, Jewargikar R. Fine needle aspiration cytology of 220 thyroid lesions histopathological correlation. Int J Res Health Sci. 2014;2(1):243-53.

Agarwal K, Puri V, Singh S. Critical appraisal of FNAC in the diagnosis of primary papillary carcinoma arising in thyroglossal cyst; a case report with review of literature on FNAC and its diagnostic pitfalls. J cyto. 2010;27:22-5.

Mahar SA, Hussain A, Islam N. Fine needle aspiration cytology of thyroid nodule: diagnostic accuracy and pitfalls. J Ayub Med Coll Abbottabad. 2006;18(4):26-9.

Pandey P, Dixit A, Mahajan NC. Fine needle aspiration of the thyroid: a cytohistologic correlation with critical evaluation of discordant cases. Thyroid research and practice. 2012;9:32-9.

Sharma C. Diagnostic accuracy of fine needle aspiration cytology of thyroid and evaluation of discordant cases. J Egypt Nat Cancer Inst. 2015; 27(3):147-53.

Hajmanoochehri F, Rabiee E. FNAC accuracy in diagnosis of thyroid neoplasms considering all diagnostic categories of the Bethesda reporting system: A single-institute experience. J Cytol. 2015; 32(4):238-43.

Shukla S, Tiwari SK. Clinicopathological evaluation of thyroid swelling in patient attending Hamidia Hospital Bhopal. Int Surg. 2020;7:2222-5.

Downloads

Published

2021-12-23

Issue

Section

Original Research Articles